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Publication:Cogo2015detector
Abstract Finding the balance between privacy protec Finding the balance between privacy protection and data sharing is one of the main challenges in managing human genomic data nowadays. Novel privacy-enhancing technologies are required to address the known disclosure threats to personal sensitive genomic data without precluding data sharing. In this paper, we propose a method that systematically detects privacy-sensitive DNA segments coming directly from an input stream, using as reference a knowledge database of known privacy-sensitive nucleic and amino acid sequences. We show that adding our detection method to standard security techniques provides a robust, efficient privacy-preserving solution that neutralizes threats related to recently published attacks on genome privacy based on short tandem repeats, disease-related genes, and genomic variations. Current global knowledge on human genomes demonstrates the feasibility of our approach to obtain a comprehensive database immediately, which can also evolve automatically to address future attacks as new privacy-sensitive sequences are identified. Additionally, we validate that the detection method can be fitted inline with the NGS---Next Generation Sequencing---production cycle by using Bloom filters and scaling out to faster sequencing machines. scaling out to faster sequencing machines.
Address Denver, CO, US  +
Author Vinicius Vielmo Cogo + , Alysson Bessani + , Francisco M. Couto + , Paulo Verissimo +
Booktitle Proceedings of the Workshop on Privacy in the Electronic Society (WPES 2015)  +
Document Cogo2015detector.pdf +
Key Cogo2015detector  +
Month oct  +
NumPubDate 2,015.1  +
Project Project:BioBankCloud +
ResearchLine Fault and Intrusion Tolerance in Open Distributed Systems (FIT) +
Title A High-Throughput Method to Detect Privacy-Sensitive Human Genomic Data  +
Type inproceedings  +
Year 2015  +
Has improper value forThis property is a special property in this wiki. Url  +
Categories Publication  +
Modification dateThis property is a special property in this wiki. 3 August 2015 13:37:56  +
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